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Re: shortness of breath with Tykerb
I had Tykerb( 5 daily) in combination with Xeloda (4 daily I think) and the side effects (vomiting diahoerrea, mouth ulcers) were so severe I was hospitalised twice with dehydration. I had to stop for a few days each time. It had a very good effect on my liver mets so I resumed at a lower dose (3 /day of Tykerb and 3 /Xeloda). It was still effective for a good while. I am now back on Tykerb (combination below) but only ever take 3/ day and have a few says off every couple of weeks as I get broken skin and very dry eyes, sometimes hand/foot syndrome. It is worth persisting with Tykerb at lower doses if it is having the desired effect on the cancer. I hope your sister is going well, she is lucky to have you on her team,
Trish
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5/2004 (R) 30mm bre gr3 infiltrating ductal ca 16/18nodes er (2+) pr (3+) HER2 (3+)
6/2004 6 cycles(FEC), Oct 40 rads, Tamoxifen
5/2006 oopherectomy, Arimedex
12/2006 liver mets largest 9cm
1/2007 Herceptin,
3/2007 Taxol + Herc
1/2008 Herc alone
4/2008 Multiple bone mets,Zometa
7/2008 Herc + Gemcitabine
8/2008 Herc+Navelbine/vinoralbine
10/2008 Herc+Carboplatin+Taxol
12/2008 Tykerb+Xeloda
2/2010 Herceptin + trial drug
5/2010 Herceptin+Tykerb
8/2010 Tykerb+Abraxane
9/2010 Abraxane
12/2010 Abraxane+Tyk+Herc
4/2011 Tyk+Herc+Femara
6/2011 Liver and bone mets prog.Abraxane continue Herceptin,Tykerb,Femara and Zometa
8/2011 Probable liver progression and increased neuropathy. Xeloda with Tyk+Herc. Zometa 6 weekly.
9/2011 Liver progression,TM +++. Cyclophosphamide and Methotrexate metro Herc Zometa
10/2011 liver mets prog.Herc, 3 Tykerb +2mg decodron daily,Zometa
Last edited by Trish; 05-05-2011 at 01:23 AM..
Reason: Proof reading
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