[pamuk]

Thank you all so much for your input and your support. Pam stopped taking Tykerb for a week because the side effects were so severe and the breathlessness went away almost straight away. She is now taking it again, and the wheeze is back. Her doc thinks that it somehow triggers her asthma which she has had for years.
She has severe nausea and diarrhea again and is thinking of stopping taking it although she is pretty much out of options. I am thinking that if she reduced the dose (she is taking 5 a day) and built up slowly it might help? If anyone has any thoughts I would be so grateful.
Best wishes
Leigh