Maybe this will help:
XELODA hand foot syndrome:
Basically, the Xeloda has a way of leaking into healthy tissues and goes to the extremities.
Things that seem to help:
Udder Cream (available at Wal-Mart) Note: apply liberally but GENTLY. Vigorous rubbing can aggravate things. Apply a few times throughout day. Good to goop it on at night and wear cotton socks or gloves to keep it there.
B6 supplement, 200mg/day
" The addition of pyridoxine (
200 mg/day) for ameliorating the symptoms of CAP-induced HFS allows for the administration of higher doses of CAP"
Topical Henna, purchase here:
www.castleart.com
discussed here:
http://xelodasideeffects.blogspot.com/
Interesting anecdote: "Henna is a natural antiseptic and the chemical in henna fills the skin cell thus it can keep hands from cracking . Field workers in India would dig small recesses in the dirt fill with henna & water ans dip their hands & feet in the mix to help prevent the skin from cracking and keep other nasty bacteria away."
Generic generic neosporin from Walgreens helps for splits.
Staying off feet as much as possible until things calm down may help.
Some suggestion that 5FU/Xeloda may be better tolerated at night. could try taking most of the Xeloda before bed.
Try all the above before approaching docs since they may only offer dose reduction.
Lengthy article about 5FU (active component of Xeloda) which gives a great overview of where Xeloda came from and hints at newer variations on the way (S-1)
http://theoncologist.alphamedpress.o...t/full/7/4/288