Pam, let's not wait and see if Onc is willing to plead your case to Genentech for compassionate T-DM1 use. If approved drugs no longer are working for you, Onc's oath to help patient should get him/her to try get you placed into Genentech's special trial.
Purpose of trial is to:
http://www.fda.gov/ForConsumers/ByAu...gs/default.htm
Sites partaking, eligibility criteria and further specifics:
http://www.clinicaltrials.gov/ct2/sh...=t-dm1&rank=11