View Single Post
Old 09-07-2012, 10:13 AM   #59
Debbie L.
Senior Member
 
Debbie L.'s Avatar
 
Join Date: Jul 2006
Posts: 463
Re: Gammaknife, Tykerb...reality check

Thanks for the update, Denise. As everyone else has said, it's always good to hear from you.

Re: empty stomach and tykerb, I remember something in the last few years about a few studies that showed food in the stomach INCREASED the absorption or availability of Tykerb, so that (in theory) a smaller dose would be used if Tykerb were taken with meals. But the counter to this was, if I recall correctly (always a big IF) -- that all the studies and calculations had been done with empty stomachs and thus it would be to too iffy to to adjust the dosing regime now, without basically starting from scratch. I wonder why they chose empty stomach back in the beginning.

Sorry I don't have time to look into this and supply references right now, but maybe someone else is interested enough to enlighten us.

Debbie Laxague
Debbie L. is offline   Reply With Quote