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I had 3 oncs tell me to have ovarian suppresion in order to take an AI because the outcome was much better. Although estrogen production can be suppressed in the ovaries by drugs or removal, your adrenal glands still produce estrogen. Thus, the reason for AIs. For me, the choice was easy, as my husband and I knew we were done having kids. I was 40. Actually, it was a relief since my hubbie was too chicken to get a vastectomy. I received 2 rounds of Lupron shots while my body recovered a bit from chemo and breast reconstruction. The oopherectomy was sooooo simple. Up and moving, slowly, the next day. Able to attend a girl's weekend (with dr permission) the next week! That was 3 years ago. About a year ago, I began Vagifem due to vaginal dryness and atrophy. Hot flashes are minimal and no muscle pain/stiffness. I,too, exercise/stretch every day. I am on Femara. My mom is also on femara (although Her2-) without issues.
Cheryl
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