HER2 Support Group Forums - View Single Post - RB...n-3 fatty acids & gene expression

R.B. · 06-09-2006, 04:24 PM

Here is another one involving the same author.

RB

http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

1: Curr Opin Lipidol. 2005 Feb;16(1):11-8. Related Articles, Links
Click here to read
Omega-3 fatty acids: molecular approaches to optimal biological outcomes.

Seo T, Blaner WS, Deckelbaum RJ.

Department of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, 630 W. 168th Street, New York, NY 10032, USA.

PURPOSE OF REVIEW: This review discusses recent advances in delineating basic mechanisms underlying the beneficial effects of omega-3 fatty acids on health and on disease. RECENT FINDINGS: While a substantial number of studies have delineated many differences between the biological effects of saturated versus polyunsaturated fatty acids, less is known about the long-chain omega-3 fatty acids commonly present in certain fish oils. In this review, we focus on recent studies relating to basic mechanisms whereby omega-3 fatty acids modulate cellular pathways to exert beneficial effects on promoting health and decreasing risks of certain diseases. We will use, as examples, conditions of the cardiovascular, neurological, and immunological systems as well as diabetes and cancer, and then discuss basic regulatory pathways. SUMMARY: Omega-3 fatty acids are major regulators of multiple molecular pathways, altering many areas of cellular and organ function, metabolism and gene expression. Generally, these regulatory events lead to "positive" endpoints relating to health and disease.

Publication Types:

* Review

PMID: 15650558 [PubMed - indexed for MEDLINE]

06-09-2006, 04:24 PM	#2
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Here is another one involving the same author. RB http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum 1: Curr Opin Lipidol. 2005 Feb;16(1):11-8. Related Articles, Links Click here to read Omega-3 fatty acids: molecular approaches to optimal biological outcomes. Seo T, Blaner WS, Deckelbaum RJ. Department of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, 630 W. 168th Street, New York, NY 10032, USA. PURPOSE OF REVIEW: This review discusses recent advances in delineating basic mechanisms underlying the beneficial effects of omega-3 fatty acids on health and on disease. RECENT FINDINGS: While a substantial number of studies have delineated many differences between the biological effects of saturated versus polyunsaturated fatty acids, less is known about the long-chain omega-3 fatty acids commonly present in certain fish oils. In this review, we focus on recent studies relating to basic mechanisms whereby omega-3 fatty acids modulate cellular pathways to exert beneficial effects on promoting health and decreasing risks of certain diseases. We will use, as examples, conditions of the cardiovascular, neurological, and immunological systems as well as diabetes and cancer, and then discuss basic regulatory pathways. SUMMARY: Omega-3 fatty acids are major regulators of multiple molecular pathways, altering many areas of cellular and organ function, metabolism and gene expression. Generally, these regulatory events lead to "positive" endpoints relating to health and disease. Publication Types: * Review PMID: 15650558 [PubMed - indexed for MEDLINE]