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Old 02-23-2010, 04:20 PM   #1
v-ness
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Join Date: Nov 2009
Location: western ma
Posts: 280
percentage of those who respond to Herceptin

hi -

on a cross-country plane trip recently i read the book HER2. chalk it up to chemo brain and too many hours on a plane, but i didn't ever quite grasp what PERCENTAGE of women with HER2+ breast cancer respond to herceptin. when i started Herceptin i guess i assumed the response rate would be, i don't know, something like 80% since it is hailed as a miracle drug. i imagine that i picked that nice number out in my mind because that's what i wanted to think. my oncologist must think i am an ingrate because i told her today i "wasn't that impressed" with numbers i read in HER2. she was surprised and drew me a graph of how drugs usually affect cancer and then how dramatically Herceptin affected by comparison. she told me about ASCO and how when the results were shown there was a collective intake of breath by 18,000 people.

but i am totally ignorant! i only got introduced to breast cancer in august! before then i didn't even know there were different kinds of breast cancer, nevermind HER2. so to me a "Miracle Drug" would be one that saved like - my magic number - 80% of lives. she told me today that it works 50% of the time. again, i hate to sound like an ingrate - i mean of course 50% is better than what preceded it! i'm sure it's staggering to an oncologist. but to a woman who had it in her chest, i'd like better than 50/50 odds it will work. again, i want to stress that i am extremely grateful for it because when i first looked up HER2+ before i got to see an oncologist i had a panic attack complete with hyperventilating. then i heard about Herceptin and was hugely relieved thinking, without question, this will work!

so today i sat in the infusion lounge thinking, for the first time (i know, i am an idiot), wow there's a 50% chance this is not working for me and that was a scary thought. i have to tell myself "hey dumbass, remember when you were hyperventilating about 'poor prognosis'? this is a hell of a lot better!" i know, some of you are probably thinking 'how could you be so naive?' but i heard Miracle Drug and thought higher than 50/50. i am laughing at myself even now. when i got diagnosed i immediately thought Cancer = Death because my bob died 10 wks after diagnoses. i have SUCH a better prognosis being stage 1 breast cancer and with Herceptin, i have no right to feel scared over a 50% number.

if that number is even correct... is it?

valerie
__________________
8/09 - IDC 1.8 cm triple positive, lumpectomy left breast
10/09 began chemo (taxotere & carboplatin) and weekly herceptin.
1/21/10 finished chemo, continued on herceptin every 3 weeks until 10/2010.
2/10 began 7 wks of radiation
6/10 mom dies of primary peritoneal ovarian cancer
8/10 got my last remaining ovary out
10/10 mammogram all clear
3/11 MRI shows 5 'spots' in right breast, largest 1 cm unidentifiable on US
needle biopsy proved the largest to be old inflamed cyst -phew!
7/10 switched to Arimidex
8/9 switched to Femara - allergic to arimidex
Femara made me lose hair quickly so switched to Aromasin
Aromasin made my hair fall out too and the bone pain was too much.
back on Tamoxifen 1/2013.
blood clot from trains and planes 5/2014 so on coumadin per onco for as long as i am on tamoxifen
tamoxifen was supposed to be up with my 5 yrs in may but my boyfriend was diagnosed with stage 4 colon cancer so i am staying on tamoxifen indefinitely because i want some ammo against BC, given the stress. lost my husband in only 10 wks in 2007 to stage 4 esophageal cancer.
cancer's screwing with another man i love
2/2016 - 6yrs in remission, off tamoxifen and off coumadin - yay!
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