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Sally/Joyce,
I too have brain mets. I was diagnosed with them on my seventh month of T-DM1.Had to stop T-DM1.
I have just finished with my second CYBERKNIFE round. I was first put on HERCEPTIN every three weeks, TYKERB 5 pills/day. It did not work. Metronomic CYTOXAN has just been added a couple of months ago. I am sistemically progressing nevertheless.
My oncologist refuses to put on AVASTIN, in spite of the fact that it appears the only way to go with brain metastases, she says that it causes brain hemorage, she says she would jeopardize her medical license if she does put me on AVASTIN. I would love to hear if other have their oncologist with the same opinion. PATRICIA