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Jackie07 · 04-08-2015, 10:37 AM

Hi,

Have you done the BRCA1 and BRCA2 genetic testing?

I had a total hysterectomy/oophorectomy 3 years after I had been treated for BC recurrence. The surgery was approved based on personal and family cancer history (Lynch Syndrome) and BRCA test result. After the surgery, the surgeon told us that the uterus was already showing hyperplesia (thickening of the wall?) Thought I would be switched to an AI after the surgery, but the oncologist wanted me to complete five years worth of Tamoxifen. Then a new doctor arrived right around the five year mark and switched me to Exemestane (trade name Aromasin).

There are more side effects of AIs. Although I've never really experienced much either with Tamoxifen or AI - possibly due to my very injured brain (two brain tumor surgeries and the chemo impacts from two breast cancer chemotherapies).

Tamoxifen works mainly on the the Estrogen in the breast area. AIs would deplete all the Estrogen everywhere in the body (there are other stuff in the body that can be converted into Estrogen after menopause). Either way, be sure to exercise regularly/often and eat a well-balanced diet. I eat a lot of oatmeal with nuts and fruit plus yogurt and milk. So far so good.

04-08-2015, 10:37 AM	#7
Jackie07 Senior Member Join Date: Jan 2008 Location: "Love never fails." Posts: 5,808	Re: hysterectomy/ooph..to change to AI Hi, Have you done the BRCA1 and BRCA2 genetic testing? I had a total hysterectomy/oophorectomy 3 years after I had been treated for BC recurrence. The surgery was approved based on personal and family cancer history (Lynch Syndrome) and BRCA test result. After the surgery, the surgeon told us that the uterus was already showing hyperplesia (thickening of the wall?) Thought I would be switched to an AI after the surgery, but the oncologist wanted me to complete five years worth of Tamoxifen. Then a new doctor arrived right around the five year mark and switched me to Exemestane (trade name Aromasin). There are more side effects of AIs. Although I've never really experienced much either with Tamoxifen or AI - possibly due to my very injured brain (two brain tumor surgeries and the chemo impacts from two breast cancer chemotherapies). Tamoxifen works mainly on the the Estrogen in the breast area. AIs would deplete all the Estrogen everywhere in the body (there are other stuff in the body that can be converted into Estrogen after menopause). Either way, be sure to exercise regularly/often and eat a well-balanced diet. I eat a lot of oatmeal with nuts and fruit plus yogurt and milk. So far so good. __________________ Jackie07 http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2 NICU 4.4 LB Erythema Nodosum 85 Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d 3 Infertility tmts 99 > 3 u. fibroids > Pills CN 3 GKRS 52301 IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET 6 TCH Cellulitis - Lymphedema - compression sleeve & glove H w x 4 MUGA 51 D, J 49 M Diastasis recti Tamoxifen B. scan Irrtbl bowel 1'09 Colonoscopy 313 BRCA1 V1247I hptc hemangioma Vertigo GI - > yogurt hysterectomy/oophorectomy 011410 Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk DEXA 1/13 1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer. 3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer. Start Vitamin D3 and Calcium supplement （600mg x2) 10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016 7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence. 7-10-2019 CT to check lung nodule. 1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule. "I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa Advocacy is a passion .. not a pastime - Joe Last edited by Jackie07; 04-08-2015 at 10:45 AM..