HER2 Support Group Forums - View Single Post - research on which breast cancer patients get CNS mets

heblaj01 · 07-19-2006, 02:00 PM

The association between metastatic brain cancer & HER2/neu status has been attributed by several medical commentators to one or more of the following factors:
-if treatment is Herceptin alone, the brain is not protected due to the blood-
barrier preventing Herceptin from reaching lesions.
- with Herceptin fighting successfully extra cranial tumours,patients are living
longer NED which leaves more time for brain metastases to develop.
- HER2 positive cancer being in the category of agressive cancers is likely to
arise more frequently whenever it is not adequately prevented/treated.

07-19-2006, 02:00 PM	#2
heblaj01 Senior Member Join Date: Apr 2006 Posts: 543	Brain tumours associated with HER2/neu status The association between metastatic brain cancer & HER2/neu status has been attributed by several medical commentators to one or more of the following factors: -if treatment is Herceptin alone, the brain is not protected due to the blood- barrier preventing Herceptin from reaching lesions. - with Herceptin fighting successfully extra cranial tumours,patients are living longer NED which leaves more time for brain metastases to develop. - HER2 positive cancer being in the category of agressive cancers is likely to arise more frequently whenever it is not adequately prevented/treated.