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I started on Xeloda and Tykerb together. The side effects were bad enough to drop the Xeloda and reduce Tykerb to 4 a day. The side effects went away for the most part. So, I was on Tykerb only for about 3 months. However, my tumor markers started back up. So, we started back on the combination. The side effects (all the usual) are coming back. So for me, Tykerb only - 4 pills seem to have minimal side effects. I tried a couple of times to increase back to 5, but the side effects came back.
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