HER2 Support Group Forums - View Single Post - Cannabinoid receptors – main ligands are Omega 3 and 6 derivatives, not hemp products

R.B. · 10-14-2019, 09:11 AM

Yes this is primarily looking at THC, but the impact is due to intervention in the cannabinoid pathways - were studies looked at impact of THC in cannabis; to what extent were they reflecting the co-impact of other cannabinoids. In the words of others:

"it is imperative that significant efforts be immediately dedicated to evaluating the potential consequences of exposure for the fetus. 2017/2018 "

Cannabis Use during Pregnancy: Pharmacokinetics and Effects on Child Development

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211194/

"Given the possibility of increased use in pregnant women and the fact that cannabis is being widely investigated as a novel treatment for a variety of diseases, including epilepsy, multiple sclerosis and cancer, it is imperative that significant efforts be immediately dedicated to evaluating the potential consequences of exposure for the fetus."

"The eCB signaling system plays an overarching regulatory role during the initial stages of embryo development, implantation and ensuing prenatal development and differentiation. It undergoes a drastic switch in function from the prenatal determination of cell fate to the homeostatic regulation of metabolic pathways and transmission in the mature CNS. The functional role of CB1R and CB2R during this early stage of embryogenesis is not well understood but is likely linked to their ability to control cell proliferation and differentiation (Galve-Roperh et al., 2013)."

10-14-2019, 09:11 AM	#8
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: Cannabinoid receptors – main ligands are Omega 3 and 6 derivatives, not hemp prod Yes this is primarily looking at THC, but the impact is due to intervention in the cannabinoid pathways - were studies looked at impact of THC in cannabis; to what extent were they reflecting the co-impact of other cannabinoids. In the words of others: "it is imperative that significant efforts be immediately dedicated to evaluating the potential consequences of exposure for the fetus. 2017/2018 " Cannabis Use during Pregnancy: Pharmacokinetics and Effects on Child Development https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211194/ "Given the possibility of increased use in pregnant women and the fact that cannabis is being widely investigated as a novel treatment for a variety of diseases, including epilepsy, multiple sclerosis and cancer, it is imperative that significant efforts be immediately dedicated to evaluating the potential consequences of exposure for the fetus." "The eCB signaling system plays an overarching regulatory role during the initial stages of embryo development, implantation and ensuing prenatal development and differentiation. It undergoes a drastic switch in function from the prenatal determination of cell fate to the homeostatic regulation of metabolic pathways and transmission in the mature CNS. The functional role of CB1R and CB2R during this early stage of embryogenesis is not well understood but is likely linked to their ability to control cell proliferation and differentiation (Galve-Roperh et al., 2013)." Last edited by R.B.; 10-16-2019 at 01:24 PM..