Thread
:
Estrogen Replacement in Menopause. NCI
View Single Post
05-21-2014, 10:13 AM
#
2
'lizbeth
Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
Re: Estrogen Replacement in Menopause. NCI
Slide 23
Estrogen Plus Progestin Replacement
Studies carried out in the 1980s suggested that adding the hormone progesterone to estrogen could offset the increased risk of uterine cancer linked to the use of estrogen by itself. For this reason, hormone replacement therapy using estrogen plus progestin (a synthetic form of progesterone) became a common way of treating women with menopausal symptoms.
However, a study of 16,000 menopausal women carried out by the Women’s Health Initiative was prematurely halted in 2002 when preliminary results indicated that the harm associated with this type of treatment outweighs the potential benefits. The major risks detected were an increased chance of developing invasive breast cancer, as well as an increased risk of strokes, heart attacks, and blood clots. While the data also revealed that hormone replacement with estrogen plus progestin lowered the risk of osteoporosis and colon cancer, these benefits were not considered to be sufficient to outweigh the other risks.
'lizbeth
View Public Profile
Send a private message to 'lizbeth
Find More Posts by 'lizbeth