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Old 03-28-2012, 03:50 PM   #1
Mandamoo
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Join Date: Jul 2011
Location: Melbourne, Australia
Posts: 432
Adjuvant herceptin 6 months vs 12 months?

Hi all
I am asking this question for a friend who is having some trouble accessing the board.

My friend is currently undergoing adjuvant therapy and is taking herceptin 3 weekly. She is interested in the benefits of 12 months vs 6 months - we cannot find any published data yet. Does anyone here know of the perceived benefit when continuing for the 12 months over 6 months? Would node status and tumor size be a factor to consider?

Hoping someone has some information for my friend.
Thanks,
Amanda
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Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis

June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions

Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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