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Nguyen · 08-10-2010, 08:55 PM

Well, the hope is her tumour would behave like below pattern, however I am not sure about given her estradiol again in the future, given the risk of it stimulating something else.

Nguyen

"In a subset of patients who were retreated with an AI after responding to estradiol, some responded and stabilized for a year or so. This included one patient who responded to 6 mg estradiol for 48 weeks, then progressed and resumed exemestane, which resulted in disease control for another 36 weeks. She progressed again and was retreated with estradiol for 12 weeks. She is now being treated with fulvestrant, Dr. Ellis said, calling this component of the study "a work in progress."

08-10-2010, 08:55 PM	#15
Nguyen Senior Member Join Date: Nov 2005 Posts: 523	Re: Counterintuitive, estradiol as treatment Well, the hope is her tumour would behave like below pattern, however I am not sure about given her estradiol again in the future, given the risk of it stimulating something else. Nguyen "In a subset of patients who were retreated with an AI after responding to estradiol, some responded and stabilized for a year or so. This included one patient who responded to 6 mg estradiol for 48 weeks, then progressed and resumed exemestane, which resulted in disease control for another 36 weeks. She progressed again and was retreated with estradiol for 12 weeks. She is now being treated with fulvestrant, Dr. Ellis said, calling this component of the study "a work in progress."