HER2 Support Group Forums - View Single Post - Clinical trial for Pre menopausal Women who are ER+, PR+ to compare tamoxifen with ov

Lori L · 11-15-2006, 06:25 AM

Thanks for the update Astrid. Its so helpful to hear the paths that others like me are taking.

For now, I think I have decided against the SOFT Trial because I am too much of a control freak to get comfortable with the randomization.

I am awaiting genetic testing results. Obviously, those results could make my decision for me.

In the meantime, other than recommending the SOFT Trial, the three oncologists I've seen have all recommended the Tamoxifen. I still have concern about the Tamoxifen resistence and cross-talk issues, but it seems like those issues are not as likely to arise while I'm on both Tamoxifen and Herceptin. That gives me until next summer to reevaluate and decide whether I want to continue on the Tamoxifen.

11-15-2006, 06:25 AM	#7
Lori L Junior Member Join Date: Oct 2006 Posts: 2	SOFT Trial Thanks for the update Astrid. Its so helpful to hear the paths that others like me are taking. For now, I think I have decided against the SOFT Trial because I am too much of a control freak to get comfortable with the randomization. I am awaiting genetic testing results. Obviously, those results could make my decision for me. In the meantime, other than recommending the SOFT Trial, the three oncologists I've seen have all recommended the Tamoxifen. I still have concern about the Tamoxifen resistence and cross-talk issues, but it seems like those issues are not as likely to arise while I'm on both Tamoxifen and Herceptin. That gives me until next summer to reevaluate and decide whether I want to continue on the Tamoxifen.