HER2 Support Group Forums - View Single Post - Other things you can do when dealing with brain mets

agness · 01-25-2016, 12:06 PM

Soapberry (and Soursop)

Soapberry fruits and even soursop are both know for lowering blood glucose and have been associated with hypoglycemic conditions on the body in malnourished individuals or those who eat too much. There is a place though for these fruits to help reduce brain blood glucose in a state of ketosis -- it just hasn't been studied yet from what I can see. There is a secondary action there which also can aid the body in fighting brain tumors but the amount needed needs to be established, what is termed "encephalitis" in other quantities I believe could help and be beneficial to the brain. This is all in addition to standard oncology treatments of course.

Here are some links to check out:

Lychee is a member of the soapberry (sapindaceae) family. This page has lots of examples if you look under notable species.
https://en.m.wikipedia.org/wiki/Sapindaceae
https://en.m.wikipedia.org/wiki/Lychee

Soursop also lowers glucose through a similar action:
https://www.mskcc.org/cancer-care/in...herbs/graviola

They have identified that members of the soapberry family are associated with illness when taken in large quantities:
https://www.chinaabout.net/be-careful-of-litchi-disease-no-more-than-300g-of-litchi-per-day/
http://wwwnc.cdc.gov/eid/article/21/5/14-1650_article
http://www.ncbi.nlm.nih.gov/pubmed/25632950
https://en.m.wikipedia.org/wiki/Ackee-- look under toxicity

They have isolated some of the active elements in lychee including methylenecyclopropylglycine and hypoglycin A.

Quantification of metabolites for assessing human exposure to soapberry toxins hypoglycin A and methylenecyclopropylglycine
http://www.ncbi.nlm.nih.gov/pubmed/26328472
Mechanism of hypoglycaemic action of methylenecyclopropylglycine
http://www.ncbi.nlm.nih.gov/pubmed/2730593

I stumbled across these by accident in this context of lowering brain glucose levels and I'm using them myself judiciously. From what I can tell they haven't thought of this connection.

01-25-2016, 12:06 PM	#11
agness Senior Member Join Date: Aug 2014 Location: Seattle, WA Posts: 285	Re: Other things you can do when dealing with brain mets Soapberry (and Soursop) Soapberry fruits and even soursop are both know for lowering blood glucose and have been associated with hypoglycemic conditions on the body in malnourished individuals or those who eat too much. There is a place though for these fruits to help reduce brain blood glucose in a state of ketosis -- it just hasn't been studied yet from what I can see. There is a secondary action there which also can aid the body in fighting brain tumors but the amount needed needs to be established, what is termed "encephalitis" in other quantities I believe could help and be beneficial to the brain. This is all in addition to standard oncology treatments of course. Here are some links to check out: Lychee is a member of the soapberry (sapindaceae) family. This page has lots of examples if you look under notable species. https://en.m.wikipedia.org/wiki/Sapindaceae https://en.m.wikipedia.org/wiki/Lychee Soursop also lowers glucose through a similar action: https://www.mskcc.org/cancer-care/in...herbs/graviola They have identified that members of the soapberry family are associated with illness when taken in large quantities: https://www.chinaabout.net/be-careful-of-litchi-disease-no-more-than-300g-of-litchi-per-day/ http://wwwnc.cdc.gov/eid/article/21/5/14-1650_article http://www.ncbi.nlm.nih.gov/pubmed/25632950 https://en.m.wikipedia.org/wiki/Ackee-- look under toxicity They have isolated some of the active elements in lychee including methylenecyclopropylglycine and hypoglycin A. Quantification of metabolites for assessing human exposure to soapberry toxins hypoglycin A and methylenecyclopropylglycine http://www.ncbi.nlm.nih.gov/pubmed/26328472 Mechanism of hypoglycaemic action of methylenecyclopropylglycine http://www.ncbi.nlm.nih.gov/pubmed/2730593 I stumbled across these by accident in this context of lowering brain glucose levels and I'm using them myself judiciously. From what I can tell they haven't thought of this connection. __________________ Dx 2/14 3b HER2+/HR- left breast, left axilla, internal mammary node (behind breast bone). Neoadjuvant TCHP 3/14-7/2. PCR 8/14 LX and SND. 10/21-12/9 Proton therapy to chest wall. Dx 7/20/15 cerebellar met 3.5x5cm HER2+/HR-/GATA3+ 7/23/15 Craniotomy. 7/29/15 bone scan clear. 8/3/15 PET clean scan. LINAC SRS (5 fractions) Sept 2015. 9/17/15 CSF NED, 9/24/15 CSF NED, 11/2/15 CSF NED. 10/27/15 atypical uptake in right cerebellum - inflammation? 12/1/15 Leptomeningeal dx. Starting IT Herceptin. 1/16 - 16 fractions of tomotherapy to cerebellum, break of IT Herceptin during rads, resume at 100 mg weekly 3/2016 - stable scan 5/2016 stable scan 7/2016 pseudoprogression? 9/2016 more LM, start new chemo protocol and IV therapy treatment with HBOT 11/2016 Cyberknife to temporal lobe, HBOT just prior 12/2016 - lesions starting to show shrinkage 8/2017 - Stable since Dec 2016. Temporal lobe lesion gone. Using TCM, naturopathic oncology, physical therapy, chiro, massage, medical qigong, and energetic healing modalities in tandem. Stops at nothing. Mother of 2 boys - ages 7 and 10 (8/2017) and a lovely partner with lots to live for. Last edited by agness; 01-25-2016 at 12:06 PM.. Reason: spacing