HER2 Support Group Forums - View Single Post - Other things you can do when dealing with brain mets

agness · 01-10-2016, 09:08 AM

Lower Your Blood and Spinal Fluid Glucose Levels (Ketogenic Diet)

Read my ketosis thread here: http://www.her2support.org/vbulletin...ad.php?t=64279

I am doing this through a ketogenic diet, and I believe that it is even more appropriate when dealing with brain mets. While being in ketosis is often as described as "starvation mode" it is a normal metabolic state for our bodies that we pass through, typically during the overnight period. What isn't normal is the high levels of glucose readily available in our diets that cause us to have glucose dysregulation, insulin resistance, and inflammation throughout our bodies.

What is interesting to me is that there are certain parallels that I have observed with this diet:

1) it is nutrient-dense and that has been a key tenet of my Chinese Medicine treatment from the beginning.

2) it matches up with anti-HER2 diet recommendations

3) it is low in potassium -- the key secondary action of taxanes, the first drugs that started really working against breast cancer, is hypokalemia -- low potassium. People have successfully committed suicide by consuming yew berries.

History of Taxols (Paclitaxol)
http://www.paclitaxel.org/background.html

The brain is normally glucose-rich, it is the normal state of the organ system. However it is easily adapted to using ketones as a fuel source. HER2 has an affinity for the brain and yet patients have observed that their HER2 brain met progression has halted when they switched their diets to keto. It isn't the be all and end all but it adds a layer to treatment that only you the patient can bring.

Each Organ Has a Unique Metabolic Profile
http://www.ncbi.nlm.nih.gov/books/NBK22436/

And, evidently, when one is in ketosis it increases the options and efficacy of hyperbaric oxygen therapy (HBOT) and can help drive IV vitamin C down deeper into the tissues.

The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
http://journals.plos.org/plosone/art...l.pone.0065522

Cancer Treatments: Is a Ketogenic Diet Better?
http://www.ketogenic-diet-resource.c...reatments.html

I'm not saying to do nothing else, I am saying do more.

01-10-2016, 09:08 AM	#5
agness Senior Member Join Date: Aug 2014 Location: Seattle, WA Posts: 285	Re: Other things you can do when dealing with brain mets Lower Your Blood and Spinal Fluid Glucose Levels (Ketogenic Diet) Read my ketosis thread here: http://www.her2support.org/vbulletin...ad.php?t=64279 I am doing this through a ketogenic diet, and I believe that it is even more appropriate when dealing with brain mets. While being in ketosis is often as described as "starvation mode" it is a normal metabolic state for our bodies that we pass through, typically during the overnight period. What isn't normal is the high levels of glucose readily available in our diets that cause us to have glucose dysregulation, insulin resistance, and inflammation throughout our bodies. What is interesting to me is that there are certain parallels that I have observed with this diet: 1) it is nutrient-dense and that has been a key tenet of my Chinese Medicine treatment from the beginning. 2) it matches up with anti-HER2 diet recommendations 3) it is low in potassium -- the key secondary action of taxanes, the first drugs that started really working against breast cancer, is hypokalemia -- low potassium. People have successfully committed suicide by consuming yew berries. History of Taxols (Paclitaxol) http://www.paclitaxel.org/background.html The brain is normally glucose-rich, it is the normal state of the organ system. However it is easily adapted to using ketones as a fuel source. HER2 has an affinity for the brain and yet patients have observed that their HER2 brain met progression has halted when they switched their diets to keto. It isn't the be all and end all but it adds a layer to treatment that only you the patient can bring. Each Organ Has a Unique Metabolic Profile http://www.ncbi.nlm.nih.gov/books/NBK22436/ And, evidently, when one is in ketosis it increases the options and efficacy of hyperbaric oxygen therapy (HBOT) and can help drive IV vitamin C down deeper into the tissues. The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer http://journals.plos.org/plosone/art...l.pone.0065522 Cancer Treatments: Is a Ketogenic Diet Better? http://www.ketogenic-diet-resource.c...reatments.html I'm not saying to do nothing else, I am saying do more.