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Old 11-04-2006, 04:50 AM   #3
Lani
Senior Member
 
Join Date: Mar 2006
Posts: 4,778
thanks Christine

this was truly relevant as I, perhaps stupidly (but always with good intent), attended a lecture at Stanford this week by David Baltimore a Nobel Prize winner and (until two months ago) President of CALTECH. It was WAY above my head in abbreviation (although he had nice slides with good diagrams with the names of all the abbreviations--compounds--and their place in the scheme of things) His lecture was on "CONTROL of NF K beta" They have found perhaps 25 pathways which feed into/out of it and he is sure they are only a small minority of them. It is a pathway that is conserved in nature--it is present in small worms, flies, rodents, etc in pretty much the same way and it is used by many systems involving wound healing, inflammation, embryogenesis, tumorigenesis.

Left feeling this was one system it would be hard to inhibit without throwing a monkeywrench in the system.

Left overwhelmed by how little we know (and this man has certainly done his part in increasing that!!)

Will pour over your article--thanks!
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