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Debbie L. · 02-23-2009, 08:34 PM

All tests, across all stages?

Bone scans, ct with and without contrast, tumor markers, mammaprint, CYP2D6 metabolism, PET, PET/CT, U/S, details of grade and growth (Scarf Bloom Richardson scale, Ki-67, S-phase, ploidy, etc). ERPR of course. Maybe topoIIa - that jury still seems to be deliberating.

For HER2 there is also CISH (not sure what its claim to fame is). And somewhere there could be the discussion of the differences among different ways to assay the same thing - like IHC for ERPR vs. Oncotype DX's quantitative RT-PCR for ERPR, and local vs. central lab pros (are there any?) and cons.

That's a start.
Debbie Laxague

02-23-2009, 08:34 PM	#5
Debbie L. Senior Member Join Date: Jul 2006 Posts: 463	All tests, across all stages? Bone scans, ct with and without contrast, tumor markers, mammaprint, CYP2D6 metabolism, PET, PET/CT, U/S, details of grade and growth (Scarf Bloom Richardson scale, Ki-67, S-phase, ploidy, etc). ERPR of course. Maybe topoIIa - that jury still seems to be deliberating. For HER2 there is also CISH (not sure what its claim to fame is). And somewhere there could be the discussion of the differences among different ways to assay the same thing - like IHC for ERPR vs. Oncotype DX's quantitative RT-PCR for ERPR, and local vs. central lab pros (are there any?) and cons. That's a start. Debbie Laxague