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Old 03-08-2011, 09:22 AM   #22
TanyaRD
Senior Member
 
Join Date: Sep 2009
Posts: 358
Re: Nutrition, exercise, and inflammation

Thank you for clarifying.
Guggul (Commifora mukul): would not be safe to take during most chemo treatments as it has the same drug-nutrient interaction as many drugs do with grapefruit. Taking Guggul with chemotherapy may make the chemo less effective. See these links.
http://en.wikipedia.org/wiki/CYP3A4
http://www.mskcc.org/mskcc/html/69249.cfm

Paederia foetida: anti-inflammatory, antidiarrheal reported uses; Couldn't find many studies and it doesn't appear to be a well researched herb/drug therefore I would be very hesitant to use it in combination with chemo/prescription meds. Here is one study I found on PubMed.
http://www.ncbi.nlm.nih.gov/pubmed/16298094

Vitex negundo: reported anti-inflammatory uses but again very little research located to support its use and safety.

Apium graveolens: found very little on this-appears to be celery (or related) and may interact with thyroid medication and increase photosensitivity to photosensitizing drugs.

Trachyspermum ammi: interestingly enough also related to celery (assume different parts of the plant) thus same risk.

Cyperus rotundus: Very little scientific info BUT I did find that it has significant antiplatelet effects (increased risk for bleeding) which could be very dangerous during chemo which often decreases platelet count anyway. I would strongly discourage its use. See this PubMed link.
http://www.ncbi.nlm.nih.gov/pubmed/21354294

Is this a blend that you have found? Based on this information I would not recommend the use of these products. If you are looking for anti-inflammatory benefits I would suggest a dietary focus with nuts, fish, fruits/vegetables, low saturated fat intake, etc. I would be happy to provide more information as desired.

Best wishes,
__________________
TanyaRD

Registered Dietitian
Board Certified Specialist in Oncology Nutrition

Last edited by TanyaRD; 03-08-2011 at 09:23 AM.. Reason: typos
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