HER2 Support Group Forums - View Single Post - Tykerb/ herception in stage 3a locally advanced patients

my2boys · 10-16-2010, 06:37 AM

I was in the Naratinib trial when I had the recurrence. The problem with that trial is that it is a double-blind placebo trial. I was on placebo, but didn't know it until I had a recurrence and even then I had to fight to be unblinded. Tykerb (Lapatinib) is in the same family of drugs as Naratinib.

Please keep in mind that I finished a year of Herceptin and then I had a recurrence within a few months time, so I needed something else besides Herceptin. The doctors at Memorial Sloan-Kettering in New York are the ones who have me on this combination of Herceptin/Tykerb. Apparently there was a clinical trial that was done here at Sloan, with good results. I was required to do the AC first and then weekly Taxol with Tykerb/Herceptin. I am currently doing rads too. I go for and echo of my heart every three months and it is doing fine so far.

Good luck with your decision.

10-16-2010, 06:37 AM	#16
my2boys Member Join Date: Dec 2008 Posts: 16	Re: Tykerb/ herception in stage 3a locally advanced patients I was in the Naratinib trial when I had the recurrence. The problem with that trial is that it is a double-blind placebo trial. I was on placebo, but didn't know it until I had a recurrence and even then I had to fight to be unblinded. Tykerb (Lapatinib) is in the same family of drugs as Naratinib. Please keep in mind that I finished a year of Herceptin and then I had a recurrence within a few months time, so I needed something else besides Herceptin. The doctors at Memorial Sloan-Kettering in New York are the ones who have me on this combination of Herceptin/Tykerb. Apparently there was a clinical trial that was done here at Sloan, with good results. I was required to do the AC first and then weekly Taxol with Tykerb/Herceptin. I am currently doing rads too. I go for and echo of my heart every three months and it is doing fine so far. Good luck with your decision.