Ah...reads more like it's an issue with breast tumors in general, not uniquely important to her2.
This part, regarding iodide in a bodily context, gets the propeller sputterin':
Quote:
|
The presence of a patient's normal thyroid will pose a challenge to the use of radioiodide to detect or treat breast tumours, as it will sequester nearly all the radioiodide until the thyroid itself is destroyed. Also, it is not yet known what proportion of human breast cancers express functional NIS and hence accumulate iodide. The results of Tazebay et al. indicate that the NIS may be incorrectly localized within the cells of some breast tumours and thus incapable of taking up iodide. So, more work is needed before we can know whether uptake of iodide in breast tumours will be of clinical use.
|