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Hopeful · 01-08-2009, 08:19 AM

Christie,

I apologize for not reading your post closely enough to see that you had mastectomy. Here is a link to an abstract from the most recent San Antonio breast conference that concluded that there was some benefit for patients who had (like you) neoadjuvant chemotherapy and mastectomy followed by radiation: http://www.abstracts2view.com/sabcs/...08L_757&terms=

I found a research article for you which describes skin reactions to rads and other radiation induced damage to DNA: http://breast-cancer-research.com/content/7/5/r690 I think this will be relevant to you, as the description of the patients in the study states: "The patients were treated with postoperative radiation therapy after mastectomy (54 patients) or with breast-conserving therapy using a standardized 60Co technique (54 patients). The dose delivered was 50 Gy over a period of 5 weeks, in daily fractions of 2 Gy (25 fractions at 5 per week). External radiation was delivered by the cobalt unit in almost all of the patients (98%), and only 2% received irradiation from a Linac 6-MV x-ray linear accelerator."

I hope this has some information that can help you with your decision.

Hopeful

01-08-2009, 08:19 AM	#8
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Christie, I apologize for not reading your post closely enough to see that you had mastectomy. Here is a link to an abstract from the most recent San Antonio breast conference that concluded that there was some benefit for patients who had (like you) neoadjuvant chemotherapy and mastectomy followed by radiation: http://www.abstracts2view.com/sabcs/...08L_757&terms= I found a research article for you which describes skin reactions to rads and other radiation induced damage to DNA: http://breast-cancer-research.com/content/7/5/r690 I think this will be relevant to you, as the description of the patients in the study states: "The patients were treated with postoperative radiation therapy after mastectomy (54 patients) or with breast-conserving therapy using a standardized 60Co technique (54 patients). The dose delivered was 50 Gy over a period of 5 weeks, in daily fractions of 2 Gy (25 fractions at 5 per week). External radiation was delivered by the cobalt unit in almost all of the patients (98%), and only 2% received irradiation from a Linac 6-MV x-ray linear accelerator." I hope this has some information that can help you with your decision. Hopeful