[phil]

my first reaction to these trials was " wow, after all these yrs, we are still looking at nasty chemos like taxotere , and a drug like tykerb, so limited in use because of the gi s/e's , as " advances " . we should be pushing for a " quick " ( whats ' quick ' in the current drug approval system ? - 2 , 3 yrs ? instead of 7 , 10 ? ) trial of neo adj. t dm-1 vs. standard of care, or neo -adj. herc /perj alone vs. herc alone .
What we really need are stage iv activist pt. /caregivers in an advocacy grp. that sits on FDA advisory boards. right now no stage iv advocacy grp gets that . instaed we have a bc action sitting on the FDA board which is so clueless that they wrote the FDA in 2010 asking them to NOT grant early appr. for t dm-1. I think an advoccay grp that has no scientific knowledge and " plays scientist " infuriates me more than the know it all Dr. Pasdur and his t dm-1 team at the FDA !