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Nancy L · 10-19-2010, 02:03 PM

Your onc feels a need for a new MRI to make sure you are on the best protocol. I do know that the Herceptin molecule is too large to cross the blood-brain barrier, which protects the brain from most things in the bloodstream. However, preliminary evidence suggests that Tykerb can cross the blood-brain barrier and enter the brain. So you may very well have to go back on Tykerb. It takes a while to get used to Tykerb but the side effects can be managed. There are several posts on this site to help you with that if they happen to you.

I hope everything turns out OK for you. I know you are scared and I wish I could say something to take thr fear away. But having been in that place myself, I know that there is nothing that anyone can say. The best thing to do is get those MRI results as quickly as possible. The unknown is scarier than the known.

10-19-2010, 02:03 PM	#3
Nancy L Senior Member Join Date: Apr 2009 Location: La Quinta, Ca Posts: 253	Re: too much research...im lost please help? Your onc feels a need for a new MRI to make sure you are on the best protocol. I do know that the Herceptin molecule is too large to cross the blood-brain barrier, which protects the brain from most things in the bloodstream. However, preliminary evidence suggests that Tykerb can cross the blood-brain barrier and enter the brain. So you may very well have to go back on Tykerb. It takes a while to get used to Tykerb but the side effects can be managed. There are several posts on this site to help you with that if they happen to you. I hope everything turns out OK for you. I know you are scared and I wish I could say something to take thr fear away. But having been in that place myself, I know that there is nothing that anyone can say. The best thing to do is get those MRI results as quickly as possible. The unknown is scarier than the known.