HER2 Support Group Forums - View Single Post - Risk of Recurrent Disease in HER2-Positive Patients

1rarebird · 03-12-2010, 08:31 AM

The opinions of the doctors reported here are indeed disturbing--particularly Dr. Goss's statement that certain data suggest that Tamoxifen may behave like an estrogen and promote breast cancer growth, or render it less effective. I am just about to begin Tamoxifen rather than an AI for reasons based on my gender and hormonal environment. Luckily I am on Herceptin at present, but like bejuice, I'm thinking that longer term Her2 receptor blockade may be the correct thing to do after my year of Herceptin ends this July. Perhaps getting in the NeratinibTrial would achieve the same thing if (and that's a big if) one receives the drug and not the placebo. More to worry about now, it seems--

bird

03-12-2010, 08:31 AM	#6
1rarebird Senior Member Join Date: Feb 2010 Location: TN Posts: 175	Re: Risk of Recurrent Disease in HER2-Positive Patients The opinions of the doctors reported here are indeed disturbing--particularly Dr. Goss's statement that certain data suggest that Tamoxifen may behave like an estrogen and promote breast cancer growth, or render it less effective. I am just about to begin Tamoxifen rather than an AI for reasons based on my gender and hormonal environment. Luckily I am on Herceptin at present, but like bejuice, I'm thinking that longer term Her2 receptor blockade may be the correct thing to do after my year of Herceptin ends this July. Perhaps getting in the NeratinibTrial would achieve the same thing if (and that's a big if) one receives the drug and not the placebo. More to worry about now, it seems-- bird __________________ Male Breast Cancer, DX 5/15/09, IDC, STAGE 1, 1.7 cm, HER2+++, ER+(95%)/PR+(75%), Ki67 40%, grade 3, 0/5 nodes, TX: mastectomy, TCH finished 7/19/10, radiation 6 wks., Tamoxifen on going, bisphosphonate 24 mos.