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Well, does it make sense on some level that most study on a her2 cell line would be on a er/pr- variant--Since the preponderance of her2+ tumors are er/pr negative?
It's been important for me to track this stuff because Rachel is er+ and pr (equivocal). So, while we're all for her using any supplements that might help, there have been a number of things (flax, ginger, milk thistle) that we've flagged because of their possible estrogenic effects.
I do wonder if the her2+/er+/pr- phenotype will start to get more attention since it's beginnign to look like it might be the one that explains a lot about the big ATAC trial and why Arimidex is coming out ahead in that one...
Best,
Jeff
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