HER2 Support Group Forums - View Single Post - "WE are confident vaccine prevents bc by preventing her2+ DCIS shows efficacy

Lani · 11-13-2006, 12:01 PM

2500 character restriction and difficulty accessing website caused the delay:
Patients began to build up reserves of white blood cells following treatment and seemed to show long-term immune responses to HER-2/neu as a result of the therapy. Of the 12 study participants, six showed markedly reduced levels of HER-2/neu expression after the vaccination, and as a result, the investigators also noted an improvement in their severity of their disease.

"The results demonstrate for the first time that this DC vaccination may have significant clinical activity against certain types of breast cancer," said Brian J. Czerniecki, M.D., of the University of Pennsylvania, and lead author of the study. "We are confident that targeted treatment with this vaccine may effectively fight not only DCIS, but may extend to prevention of breast cancer entirely."

11-13-2006, 12:01 PM	#2
Lani Senior Member Join Date: Mar 2006 Posts: 4,778	the long awaited "kicker" 2500 character restriction and difficulty accessing website caused the delay: Patients began to build up reserves of white blood cells following treatment and seemed to show long-term immune responses to HER-2/neu as a result of the therapy. Of the 12 study participants, six showed markedly reduced levels of HER-2/neu expression after the vaccination, and as a result, the investigators also noted an improvement in their severity of their disease. "The results demonstrate for the first time that this DC vaccination may have significant clinical activity against certain types of breast cancer," said Brian J. Czerniecki, M.D., of the University of Pennsylvania, and lead author of the study. "We are confident that targeted treatment with this vaccine may effectively fight not only DCIS, but may extend to prevention of breast cancer entirely."