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Old 02-18-2013, 10:22 AM   #3
rhondalea
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Join Date: Jun 2011
Location: Somerset, NJ
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Promising New Approach to Preventing Progression of Breast Cancer

I searched the site for this press release, and I found the post above instead. You were way ahead of the game, Lani.

I took nicotinamide (a/k/a niacinamide) for nearly a year several years before I was diagnosed, and then I (stupidly, in retrospect) stopped. More recently, I started taking NADH (low dose), but as soon as I read this article, I put a four months' supply straight into the trash bin. (I'm usually not such a reactionary, but it struck a nerve.) My replacement supplement (Source Naturals Coenzymated NAD) will arrive in the next few days.

Promising New Approach to Preventing Progression of Breast Cancer

The next logical step was to find a simple way to enhance the critical NAD+ level therapeutically. So the team explored what would happen if mice with breast cancer were fed water spiked with nicotinamide, a precursor for NAD+ production. The scientists found cancer development was dramatically slowed down, and the mice lived longer.


http://www.scripps.edu/news/press/20...15felding.html

I'm now off to ascertain the known pitfalls. It seems to me I remember some issues with niacin and niacinamide from the last time, but under the circumstances, I think I can live with them.

Edited to add a link to the full report:

http://www.jci.org/articles/view/64264

PDF is available.
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2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy

Last edited by rhondalea; 02-18-2013 at 10:28 AM.. Reason: add link to full report
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