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I started Gemzar and Herceptin today. Will add carboplatin if numbers don't come down after one cycle. Also, I feel great that I am now working with a world-reknowned integrative hematologist oncologist who will work with my primary. It's a new approach, and I believe, something I should've done years ago.
Back in 1999, my cat got cancer and I went the route of giving him chemo. The holistic vet I used advised me that I should not shoot the body full of chemo without boosting the immune system and taking good tumor-busting supplements. That was a lesson I didn't listen to for myself. It applies. I started with amino acid infusions and within two days I could feel the neuropathy lessening. A mouth sore gone. Main ingredient in that infusion is glutathione. When I researched it, I was ripped that I hadn't started way before this.
We are taking a multi-angled shot at the cancer, and I'm feeling good about it. It's been some time since I achieved NED status, but out to catch it again.
Also looking to retest mutations with Caris vs. Foundation One. According to their website, their testing is a bit more sensitive. Would love some feeback if anyone has experience with Caris.
Warmly,
Karen

__________________
World Trade Center Survivor (56th Floor/North Tower): 14 years and still just like yesterday.
Graves Disease, became Euthyroid via Radioactive Iodine, June 2001.
Thyroid Eye Disease. 2003. Decompression surgery in 2009; eyelid lowering surgery in 2010.
Diagnosed: June 2010, liver mets. ER-/PR+10%; HER2+++.
July 2010: Begin Taxol/Herceptin. Eliminate sugar from diet. No surgery or radiation.
January 2011: NED
April 2011: Progression in liver only. Other previous affected areas eradicated. Stop Taxol/Herceptin after 32 infusions.
May 2011: Brain MRI: clear.
May 2011: Begin Tykerb daily, Xeloda twice per day for one week on, one week off, and Herceptin.
November 2011: Progression in liver. All other tumors remain eradicated.
December 2011: BEGIN TRIAL #09-093 Taxol, MCC-DM1 (T-DM1), Perjeta.
Trial requires scans every six weeks, bloodwork and infusions weekly.
Brain MRI: clear.
January 2012: NED. Liver mets, good riddance!
March 2012: NED. Developed SMA (rare blood clot) in intestinal artery and loss of sight in right eye due to optical nerve neuropathy. Resolved when Taxol removed this month.
Continue Protocol of T-DM1 weekly and Perjeta every 3 weeks.
May 2012: NED.
June 2012: Brain MRI: clear.
June-December 2012: NED.
December 2012: TRIAL CONCLUDED; ENTER TRIAL EXTENSION #09-037. CT, Brain MRI, bone scan: clear. NED.
January-March 2013: NED.
June 2013: Brain MRI: clear. CEA upticking; CT shows new met on liver.
July 3, 2013: DISASTER STRIKES during liver ablation: sloppy surgeon cuts intercostal artery and I bleed out, lose 3.5 liters of blood, have major hemothorax, and collapsed lung requiring emergency resuscitative thoracotomy, lung surgery, rib rearrangement and cutting deep connective tissue, transfusion. Ablation incomplete. This life-saving procedure would end up causing me unforgiving pain with every movement I make, permanently, otherwise known as forever.
July 26, 2013: Try Navelbine/Herceptin. Body too weak after surgery and transfusion. Fever. CEA: Normal.
August 16, 2016: second dose Navelbine/Herceptin; CEA: Normal. Will skip doses. Watching and waiting.
September 2013: NED, Herceptin only. CEA: Normal. Started Arimidex.
October-November 2013: NED. Herceptin and Arimidex. CEA, CA125, 15-3: Normal.
December 2013: Something brewing. PET lights up on little spot on liver; CEA upward trend, just outside normal. PET and triphasic liver scan confirm Little Met. Restart Perjeta with Herceptin, stay on Arimidex. Genomic sequencing completed for future treatments, if necessary.
January 2014: Ablate Little Met on the 6th. Happy New Year.
March 2014: Brain MRI: clear. PET/CT reveal liver mets return; new lung mets. This is not funny.
March 2014: BEGIN TRIAL #10-005 A(11)-Temsirolimus plus Neratinib.
April 2014: Genomic testing indicated they could work, they did not. Very strange drug combo for me, felt weird.
April 2014: Started Navelbine and Herceptin. Needed something tried and true, but had significant progression.
June 2014: Doxil and Herceptin.
July 2014: Progression. Got nothing out of it. Brain: NED.
July 2014: Add integrative medical hematologist-oncologist to my team. Begin supplements. These are tumor-busting, immune system boosters. Add glutathione, lysine and taurine IV infusions every three weeks.
July 2014: Begin Gemzar, Herceptin & Perjeta. Happy.
August 2014: ECHO perfect.
January 2015: Begin weekly Vitamin D Analog infusions. 25 mcg. via port.
February 2015: CT: stable.
April 2015: Gem working, but not 100%. Looking into immunotherapy. Finally, treatments for the 21st century!
April 2015: Penn Medicine. Dendritic cell immunotherapy.

07-30-2014, 02:42 PM	#1
KDR Senior Member Join Date: Aug 2010 Location: New York, New York Posts: 1,580	Gemzar & Herceptin I started Gemzar and Herceptin today. Will add carboplatin if numbers don't come down after one cycle. Also, I feel great that I am now working with a world-reknowned integrative hematologist oncologist who will work with my primary. It's a new approach, and I believe, something I should've done years ago. Back in 1999, my cat got cancer and I went the route of giving him chemo. The holistic vet I used advised me that I should not shoot the body full of chemo without boosting the immune system and taking good tumor-busting supplements. That was a lesson I didn't listen to for myself. It applies. I started with amino acid infusions and within two days I could feel the neuropathy lessening. A mouth sore gone. Main ingredient in that infusion is glutathione. When I researched it, I was ripped that I hadn't started way before this. We are taking a multi-angled shot at the cancer, and I'm feeling good about it. It's been some time since I achieved NED status, but out to catch it again. Also looking to retest mutations with Caris vs. Foundation One. According to their website, their testing is a bit more sensitive. Would love some feeback if anyone has experience with Caris. Warmly, Karen __________________ World Trade Center Survivor (56th Floor/North Tower): 14 years and still just like yesterday. Graves Disease, became Euthyroid via Radioactive Iodine, June 2001. Thyroid Eye Disease. 2003. Decompression surgery in 2009; eyelid lowering surgery in 2010. Diagnosed: June 2010, liver mets. ER-/PR+10%; HER2+++. July 2010: Begin Taxol/Herceptin. Eliminate sugar from diet. No surgery or radiation. January 2011: NED April 2011: Progression in liver only. Other previous affected areas eradicated. Stop Taxol/Herceptin after 32 infusions. May 2011: Brain MRI: clear. May 2011: Begin Tykerb daily, Xeloda twice per day for one week on, one week off, and Herceptin. November 2011: Progression in liver. All other tumors remain eradicated. December 2011: BEGIN TRIAL #09-093 Taxol, MCC-DM1 (T-DM1), Perjeta. Trial requires scans every six weeks, bloodwork and infusions weekly. Brain MRI: clear. January 2012: NED. Liver mets, good riddance! March 2012: NED. Developed SMA (rare blood clot) in intestinal artery and loss of sight in right eye due to optical nerve neuropathy. Resolved when Taxol removed this month. Continue Protocol of T-DM1 weekly and Perjeta every 3 weeks. May 2012: NED. June 2012: Brain MRI: clear. June-December 2012: NED. December 2012: TRIAL CONCLUDED; ENTER TRIAL EXTENSION #09-037. CT, Brain MRI, bone scan: clear. NED. January-March 2013: NED. June 2013: Brain MRI: clear. CEA upticking; CT shows new met on liver. July 3, 2013: DISASTER STRIKES during liver ablation: sloppy surgeon cuts intercostal artery and I bleed out, lose 3.5 liters of blood, have major hemothorax, and collapsed lung requiring emergency resuscitative thoracotomy, lung surgery, rib rearrangement and cutting deep connective tissue, transfusion. Ablation incomplete. This life-saving procedure would end up causing me unforgiving pain with every movement I make, permanently, otherwise known as forever. July 26, 2013: Try Navelbine/Herceptin. Body too weak after surgery and transfusion. Fever. CEA: Normal. August 16, 2016: second dose Navelbine/Herceptin; CEA: Normal. Will skip doses. Watching and waiting. September 2013: NED, Herceptin only. CEA: Normal. Started Arimidex. October-November 2013: NED. Herceptin and Arimidex. CEA, CA125, 15-3: Normal. December 2013: Something brewing. PET lights up on little spot on liver; CEA upward trend, just outside normal. PET and triphasic liver scan confirm Little Met. Restart Perjeta with Herceptin, stay on Arimidex. Genomic sequencing completed for future treatments, if necessary. January 2014: Ablate Little Met on the 6th. Happy New Year. March 2014: Brain MRI: clear. PET/CT reveal liver mets return; new lung mets. This is not funny. March 2014: BEGIN TRIAL #10-005 A(11)-Temsirolimus plus Neratinib. April 2014: Genomic testing indicated they could work, they did not. Very strange drug combo for me, felt weird. April 2014: Started Navelbine and Herceptin. Needed something tried and true, but had significant progression. June 2014: Doxil and Herceptin. July 2014: Progression. Got nothing out of it. Brain: NED. July 2014: Add integrative medical hematologist-oncologist to my team. Begin supplements. These are tumor-busting, immune system boosters. Add glutathione, lysine and taurine IV infusions every three weeks. July 2014: Begin Gemzar, Herceptin & Perjeta. Happy. August 2014: ECHO perfect. January 2015: Begin weekly Vitamin D Analog infusions. 25 mcg. via port. February 2015: CT: stable. April 2015: Gem working, but not 100%. Looking into immunotherapy. Finally, treatments for the 21st century! April 2015: Penn Medicine. Dendritic cell immunotherapy.