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Old 08-09-2013, 06:44 AM   #14
'lizbeth
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Join Date: Apr 2008
Location: Sunny San Diego
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Re: metronomic chemo

The Ad-p53, under the brand name of Gendicine, or Advexin, has been currently in clinical use in China since 2003 [55] or in phase 1 to 3 clinical trial in the United States, respectively [7]. The results showed that Gendicine/Advexin is well tolerated in patients . . .

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822448/

Is it possible to go to China, see the Great Wall, and be cured of P53 breast cancer?

I'm not reading about good results on this one, perhaps there are more trials than the one for Introgen Therapeutics, Inc. Advexin?

I see the one on clinicaltrials.gov in Florida:

A Phase 1/2 Study of Ad.p53 DC Vaccine in Combination With 1-methyl-D-tryptophan in Metastatic Solid Tumors and Invasive Breast Cancer

(Human epidermal growth factor receptor 2 positive (HER2+) patients (IHC 3+ and/or fluorescent in situ hybridization [FISH] HER2/CEP17 ratio > 2) who require treatment with trastuzumab or lapatinib are not eligible for this study)


United States, Florida H. Lee Moffitt Cancer Center and Research Institute Recruiting Tampa, Florida, United States, 33612 Contact: Hatem H. Soliman 813-745-4933 hatem.soliman@moffitt.org Principal Investigator: Hatem H. Soliman

http://www.clinicaltrials.gov/ct2/sh...and+p53&rank=3

I'm not finding the clinical trials for Dacomitinib for breast cancer, are there other inhibitors of Pan-Her? Or other trials that didn't pop up on my search?

Last edited by 'lizbeth; 08-09-2013 at 07:01 AM.. Reason: Additions
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