HER2 Support Group Forums - View Single Post - New Endpoints Proposed for Chemotherapy in Ovarian Cancer?

gdpawel · 06-20-2013, 11:33 AM

"These measures are "the most important aims of treatment" in these patients because improvements in overall and progression-free survival (OS and PFS) have hit a ceiling in trial after trial of chemotherapies,"

Priceless Quote!

I personally think this is scandalous. What they are saying is that they are not coming up with any drugs which are any better than the drugs that they have been using all along. So big Pharma has no new drugs to sell. So they change the goal line. Or, more accurately, they lower the bar. Progression free survival and overall survival are hard objective endpoints. Quality of life is totally squishy and unobjective. So future clinical trials in cancer are going to be designed and scored by psychologists. Patients should never ever let them get away with this. Their feet should be held close to the fire. Shame on them.

06-20-2013, 11:33 AM	#2
gdpawel Senior Member Join Date: Aug 2006 Location: Pennsylvania Posts: 1,080	Those Who Can, Do - Those Who Can't, Change The Rules! "These measures are "the most important aims of treatment" in these patients because improvements in overall and progression-free survival (OS and PFS) have hit a ceiling in trial after trial of chemotherapies," Priceless Quote! I personally think this is scandalous. What they are saying is that they are not coming up with any drugs which are any better than the drugs that they have been using all along. So big Pharma has no new drugs to sell. So they change the goal line. Or, more accurately, they lower the bar. Progression free survival and overall survival are hard objective endpoints. Quality of life is totally squishy and unobjective. So future clinical trials in cancer are going to be designed and scored by psychologists. Patients should never ever let them get away with this. Their feet should be held close to the fire. Shame on them.