HER2 Support Group Forums - View Single Post - Intrathecal Herceptin/Topotecan for Leptomeningeal Disease

evlin75 · 03-09-2013, 11:48 AM

Hard to know. We were wondering about using perjeta IT. It was very difficult to find a doctor willing to do the higher dose Herceptin.
Your suggestion of TDM1 -or even pergeta - IT, might be something to consider but again unapproved and experimental so what doctor would chance trying it?
And of course the guidelines for TDM1 are such that it would not be available to her at this point.

03-09-2013, 11:48 AM	#60
evlin75 Senior Member Join Date: Sep 2007 Posts: 118	Re: Intrathecal Herceptin/Topotecan for Leptomeningeal Disease Hard to know. We were wondering about using perjeta IT. It was very difficult to find a doctor willing to do the higher dose Herceptin. Your suggestion of TDM1 -or even pergeta - IT, might be something to consider but again unapproved and experimental so what doctor would chance trying it? And of course the guidelines for TDM1 are such that it would not be available to her at this point.