[phil]

My wife got her best response prior to tdm-1 out of herceptin/gemzar. 18 months of stability. That was early in her fight, but she was Stage IV from the start. The idea is to keep surprising the cancer w/ something new.
If you try another choice, think about compassionate use as the next step, if needed. It will be about a yr until t dm-1 approval, maybe a little less if we keep the pressure on This FDA, and This Pres., in an election yr. Really, when you look at t dm-1 and avastin , His Administration has been a Disaster for Stage IV BC. Sad. And Genetech top execs making abusiness decison to deny comp. use. Shameful. Sooner or later , their actions will get the negative Public PR that they deserve. Someone will be the first , hopefully , to get comp. use. You may have to push your onc to talk w/ Gen. docs. A lot of oncs are reluctant to get into it, they know its crooked. The FDA washes its hands of it, wouldnt even talk to us . Said " Talk to your doc, have them talk w/ Genentech. Then they talk to us . We dont need ( or want ) to talk w/ you. " Un-believable. And they re-write the accelerated approval law, ignoring the people ! That single pt. /comp use system is crooked, will need changing. Too much power w. private business in that equation. They are selling life-saving meds, not computers ! In that area we need an FDA that works for Us !