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Old 10-13-2009, 04:48 PM   #19
Sandra in GA
Senior Member
 
Join Date: Aug 2009
Location: Moultrie, GA
Posts: 431
Re: Neratinib Clinical Trial

That is what I had assumed becuse they both seem to have similar side effects (diarrhea) as well as cross the the brain barrier. I was told that the Herceptin attacks the HER2 cells on the outside and the lapatinib (Tykerb) attacks the cells on the inside. From where I stand, it feels good to know that I am attacking them from almost all angles. Thank you for the info concerning Neratinid. I am unfamiliar with it.
Sandra
__________________
Diagnosed: 7/25/08 ~ age 63, no family history
Surgery: 8/14/08 Bilateral mastectomy; tumor left breast, node dissection; right prophylactic with expanders: 1/12/10 latisimuss dorsi flap on left side: 9/22/10 implants in
Pathology Report: ER/PR-; HER2+ (3+); Grade 3, StageIII; 3cm tumor plus 21/21 lymph nodes positive; 5cm DCIS
Chemo: A/C; Taxol/Herceptin/Tykerb; phase II study at Mayo adding Tykerb for early stage
Radiation: 25 rads
Vaccine: Walter Reed GP2/AE37 vaccine study ~ last booster 9/17/2012
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