HER2 Support Group Forums - View Single Post - Genentech's Trastuzumab Emtansine (T-DM1) Reduces The Risk Of Cancer Worsening

Mandamoo · 06-07-2012, 07:36 PM

I understand that it may not be a miracle but it may just be another option. We are not a herd of cows - we are all unique - it had a response in about 40% that's still a lot of women/men. What about them and those of us who may be like them? Are we to be denied an option because it may not work for others?

The sooner they can test for who will respond to what - true personalized oncology the better. How many other drugs get left on the shelf because the only work for a few?

06-07-2012, 07:36 PM	#15
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: Genentech's Trastuzumab Emtansine (T-DM1) Reduces The Risk Of Cancer Worsening I understand that it may not be a miracle but it may just be another option. We are not a herd of cows - we are all unique - it had a response in about 40% that's still a lot of women/men. What about them and those of us who may be like them? Are we to be denied an option because it may not work for others? The sooner they can test for who will respond to what - true personalized oncology the better. How many other drugs get left on the shelf because the only work for a few? __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.