HER2 Support Group Forums - View Single Post - If there's phase 3, were there p1 and p2?

Nguyen · 09-22-2008, 11:54 AM

Hello,

There is a partially blind phase 3 trial (SOFEA) comparing Fulvestrant +/- Anastrozole with Exemestane. Since it's a phase 3 trial, must there were phase 1 and 2 trials? If so, does anyone happen to know where to find results for the correspond phase 1 and 2 trials? I needed to know the effectiveness of Fulvestrant + Anastrozole. A great many thanks.

Nguyen

------------------

Linda's treatment history:
09/2008: need to change treatment
04/2008 - present: Herceptin and Exemestane
01/2008: Oophorectomy
01/2005 - 4/2008: Herceptin (readded) and Femara
07/2004: It returned again via several small nodules in the lung
10/2002: NED (via CT and CA27.29)!
10/2001 - 01/2005: Femara, Fosamax
12/2000 - 10/2001: Herceptin and Navelbine
12/2000: lung metastatic was diagnosed (a few small nodules)
02/1998 - 12/2000: Daily Tamoxifen
05/1997 - 04/1998: Modified Radical Mastectomy, many many cycles of chemo
regiments (CAF,Taxol, Carpoplatin, Thiotepa, Navelbine,
Taxotere), including HDC, and radiation
05/1997: First diagnosed with BC stage 3A, ER+, PR+, HER2 +,
poorly differetiated, nuclear grade 3.

09-22-2008, 11:54 AM	#1
Nguyen Senior Member Join Date: Nov 2005 Posts: 515	If there's phase 3, were there p1 and p2? Hello, There is a partially blind phase 3 trial (SOFEA) comparing Fulvestrant +/- Anastrozole with Exemestane. Since it's a phase 3 trial, must there were phase 1 and 2 trials? If so, does anyone happen to know where to find results for the correspond phase 1 and 2 trials? I needed to know the effectiveness of Fulvestrant + Anastrozole. A great many thanks. Nguyen ------------------ Linda's treatment history: 09/2008: need to change treatment 04/2008 - present: Herceptin and Exemestane 01/2008: Oophorectomy 01/2005 - 4/2008: Herceptin (readded) and Femara 07/2004: It returned again via several small nodules in the lung 10/2002: NED (via CT and CA27.29)! 10/2001 - 01/2005: Femara, Fosamax 12/2000 - 10/2001: Herceptin and Navelbine 12/2000: lung metastatic was diagnosed (a few small nodules) 02/1998 - 12/2000: Daily Tamoxifen 05/1997 - 04/1998: Modified Radical Mastectomy, many many cycles of chemo regiments (CAF,Taxol, Carpoplatin, Thiotepa, Navelbine, Taxotere), including HDC, and radiation 05/1997: First diagnosed with BC stage 3A, ER+, PR+, HER2 +, poorly differetiated, nuclear grade 3.