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Old 10-14-2019, 10:12 AM   #9
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
Re: Cannabinoid receptors – main ligands are Omega 3 and 6 derivatives, not hemp prod

Are CBD products bio-active in PGE2 and other pathways - yes https://www.google.com/search?client...b-d&q=CBD+PGE2

Might that have pharmacological potential in particular circumstances - yes

Are Omega 6 and 3 and downstream product pathways including COX and LOX products central in tissue creation and repair including in pregnancy - yes

Do we know what effect CBD cannabinoids are having in pregnancy and early development - no



Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action

http://www.scielo.br/scielo.php?scri...62008000300015

"In the last 45 years it has been possible to demonstrate that CBD has a wide range of pharmacological effects, many of which being of great therapeutic interest, but still waiting to be confirmed by clinical trials. It is important to highlight that many effects of CBD draw a bell-shaped dose-response curve, suggesting that the dose is a pivotal factor in CBD research. The wide range of CBD effects can be explained by the multiple mechanisms through which CBD acts, although further research is needed to clarify the precise mechanisms that underlie some of the potentially beneficial effects of CBD."

Last edited by R.B.; 10-14-2019 at 01:49 PM..
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