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al from Canada · 11-13-2006, 05:01 PM

Just remember that in a HER2 BC, the combination of herceptin + chemo is expodentially better than either one alone. That said, even if xeloda does cross the BBB, it is likely to be of little benefit if not combined with a HER2 blocker that crosses the BBB, ie, tykerb. Linda was on xeloda for over one year and still developed brain mets.

Al

11-13-2006, 05:01 PM	#7
al from Canada Senior Member Join Date: Jul 2005 Location: Ontario, Canada Posts: 722	Just remember that in a HER2 BC, the combination of herceptin + chemo is expodentially better than either one alone. That said, even if xeloda does cross the BBB, it is likely to be of little benefit if not combined with a HER2 blocker that crosses the BBB, ie, tykerb. Linda was on xeloda for over one year and still developed brain mets. Al __________________ Primary care-giver to and advocate for Linda, who passed away April 27, 2006.