HER2 Support Group Forums - View Single Post - tamoxifen and Her2

saleboat · 11-28-2006, 11:25 AM

Hi Cindy,

This issue is so confusing!

I also saw three Oncologists about hormonal treatment, and all three recommended Tamox for me. It took some time and research to get my head around it, but I'm now very comfortable with the decision. There are unknown risks to removing/shutting down one's ovaries, and given that I'm highly Er and Pr positive, the benefit of AIs is not that great vs. Tamox. I think I would make a different decision (AIs) if I only had one receptor positive because it is in this case that AIs showed the greatest benefit vs. Tamox.

Of Her2+ patients, if they are hormonally positive, they tend to have only one receptor positive. However, younger women are more likely to have both receptors positve.

Congrats on being almost 3 years out. I can imagine that the worries never really goes away, but it sounds like your highest risk time for recurrance is behind you.

Good luck,
Jen

11-28-2006, 11:25 AM	#4
saleboat Senior Member Join Date: Sep 2005 Location: NYC Posts: 250	Hi Cindy, This issue is so confusing! I also saw three Oncologists about hormonal treatment, and all three recommended Tamox for me. It took some time and research to get my head around it, but I'm now very comfortable with the decision. There are unknown risks to removing/shutting down one's ovaries, and given that I'm highly Er and Pr positive, the benefit of AIs is not that great vs. Tamox. I think I would make a different decision (AIs) if I only had one receptor positive because it is in this case that AIs showed the greatest benefit vs. Tamox. Of Her2+ patients, if they are hormonally positive, they tend to have only one receptor positive. However, younger women are more likely to have both receptors positve. Congrats on being almost 3 years out. I can imagine that the worries never really goes away, but it sounds like your highest risk time for recurrance is behind you. Good luck, Jen __________________ dx 4/05 @ 34 y.o. Stage IIIC, ER+ (90%)/PR+ (95%)/HER2+ (IHC 3+) lumpectomy-- 2.5 cm 15+/37 nodes (IVF in between surgery and chemo) tx dd A/C, followed by dd Taxol & Herceptin 30 rads (or was it 35?) Finished Herceptin on 7/24/06 Tamox livingcured.blogspot.com "Keep your face to the sunshine and you cannot see the shadow." -- Helen Keller Last edited by saleboat; 11-28-2006 at 02:24 PM.. Reason: spelling!