[Nguyen]

Thank you for all the support. After 10+ years I still didn't do any better in waiting for result. Though I was more nervous this time, since Exemestance failed her after a few months, and we just switch to Fulvestrant. Anyway, the nurse calls back and CA27.29 is about the same as before. So at least the disease is stabilized. I've been spending time updating my battle plan with the latest data from numerous conferences (2008ASCO, 2008SABCS, 2008ESMO, and cases). In case it's of use to someone with similar disease characteristics. The list is an ordered list. Keep in mind that there's no trial for the sequence, though there are data for each combination. AND of course I am not an MD.

Best wishes,

Nguyen

• 6mg of generic Estradiol therapy :
• Lapatinib + Capecitabine ;
• Lapatinib + Trastuzumab
• Bevacizumab + Trastuzumab (or Lapatinib)
• Nab Paclitaxel + Bevacizumab (plus Trastuzumab?)
• Bevacizumab + Fulvestrant (or Letrozole)
• Trastuzumab + Pertuzumab OR Lapatibib + Pazopanib
• Trastuzumab-DM1
• All chemo combination (Oral Vinorelbine and ? OR Trastuzumab+Paclitaxol+Gemcitabine?)
• Metronomic chemotherapy with a biologic