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REVIEW
Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer
* D. PEREG11Department of Internal Medicine A, Sapir Medical Center, Kfar Sava &
* M. LISHNER1,21Department of Internal Medicine A, Sapir Medical Center, Kfar Sava2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv; Israel
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From the 1Department of Internal Medicine A, Sapir Medical Center, Kfar Sava; and 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv; Israel
"Whilst their anti-inflammatory effect is well known, recent studies have demonstrated an unexpected effect in both the prevention and treatment of several types of cancer. The anticancerous effect of NSAIDs is believed to be mainly due to the inhibition of COX-2, which is overexpressed in many types of cancer and may play a major role in tumourigenesis."
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