|
To clarify -- Taxol has been proven to be extremely effective in women who are HER2+ and ER-. Adrymyician is effective for women who are HER2+ and also test postive for TOPOIIa.
Unfortunatley we can't get all the information we need in just one article. We have to sort of read them all and cut and paste to get the full picture. It's no easy task deciding what chemo should be given or what will be most effective since there are so many variables in breast cancer. Not only do you have to consider your hormone status and HER status but now they want to take into consider the TOPOII and many other elements. Perhaps one day each of us will have a customized chemo plan just made for us.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
|