[donocco]

Duoloxetine is has the same mechanism of action as Effexor
(Venaflaxine). It is a combination Serotonin Uptake and Norepinephrine reuptake inhibitor. The side effects are drowsiness, sometimes insomnia, dizziness constipation, and dry mouth. Some people have an increase in blood pressure. The liver enzymes will probably be monitored. If you can tolerate Effexor you probably will be able to tolerate Cymbalta(Duoloxetine). I wouldnt take the two together.

Paul