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Old 02-27-2016, 11:00 AM   #14
broccoli
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Join Date: Dec 2013
Location: Toronto, Canada
Posts: 26
Re: Do you take Metformin?

I've just heard from a friend on the Metformin trial who had TNBC that all ER-/PR- patients are being dropped from the trial because the latest analysis of the data has shown that Metformin has no effect on recurrence rates for that group.

I haven't yet heard from my study coordinator (my cancer was ER-/PR-/HER2+) but once I do I'll post back here.
__________________
2012-Feb-29 D-Day: IDC ER-/PR- HER2+++ Grade 3, Stage 3 - several biopsy proven positive nodes
2012-Mar - July: Neoadjuvant FEC-D + Herceptin (6 rounds)
2012-Apr: DVT in arm that received chemo - put on LMW Heparin
2012-Apr: Port installed
2012-Sep-7: Lumpectomy + ALND - pCR with residual DCIS
2012-Oct: Switched from LMW Heparin to Warfarin
2012-Oct-Nov: 30 days of rads
2013-Jan: Entered Adjuvant Metformin trial (Metformin or placebo for 5 years)
2013-Jan: Switched from Warfarin to Xarelto
2013-Mar: First signs of lymphedema
2013-May-16: Last Herceptin (17 doses in total)
2013-Jun: Port removed and anticoagulants stopped
2014-Mar: Lymphedema worsened and became unresponsive to treatment
2015-Apr: Started PENTOCLO protocol to attempt to improve radiation fibrosis
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