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R.B. · 01-26-2008, 04:02 PM

Flaxseed

Another interesting trial again with mice.

RB

"Our previous short-term study has shown that 10% flaxseed (FS) inhibits the growth of human estrogen dependent estrogen receptor positive breast tumors (MCF-7) xenografts in ovariectomized (OVX) athymic mice and enhances the tumor inhibitory effect of tamoxifen (TAM)."...

"In conclusion, after long-term treatment, FS did not stimulate tumor growth and combined with TAM, regressed tumor size in part due to downregulation of the expression of estrogen-related gene products and signal transduction pathways."

http://www.ncbi.nlm.nih.gov/pubmed/1...RVAbstractPlus

Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways.
Chen J, Power KA, Mann J, Cheng A, Thompson LU.

Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

01-26-2008, 04:02 PM	#197
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Flaxseed Another interesting trial again with mice. RB "Our previous short-term study has shown that 10% flaxseed (FS) inhibits the growth of human estrogen dependent estrogen receptor positive breast tumors (MCF-7) xenografts in ovariectomized (OVX) athymic mice and enhances the tumor inhibitory effect of tamoxifen (TAM)."... "In conclusion, after long-term treatment, FS did not stimulate tumor growth and combined with TAM, regressed tumor size in part due to downregulation of the expression of estrogen-related gene products and signal transduction pathways." http://www.ncbi.nlm.nih.gov/pubmed/1...RVAbstractPlus Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. Chen J, Power KA, Mann J, Cheng A, Thompson LU. Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.