Dear Jules:
Here's a link to a summary from about a year ago:
http://www.gotoper.com/publications/...merging-agents
And here's another good overview:
http://www.medscape.com/viewarticle/870720
There's a new drug coming along for people who are both ER and HER2 positive that looks quite promising. It's called tucatanib.
That being said, I see no reason not to try Kadcyla (a/k/a TDM-1).
While I wait around for something new to be approved (or for a study. . . .) I'm doing Herceptin and Eribulin. I have mets in my lungs and in one vertebra. My bone met doesn't seem to respond to HER2 targeted therapies.
There are other classes of chemo that can be given with Herceptin. And novel combinations can be tried.
Hang in there! I'm so glad you feel good and your blood tests are good.
Amy