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Re: Decisions, decisions...
Good news Annette! I "gave up" after 6 rounds of Docetaxol, as I found the cumulative effects of a low immune system and general weakness too much to bear. However it seemed to have done the trick, as the bone mets were sclerotic and my liver mets shrank to "almost immeasurable and most likely inactive". I have continued stable on Herceptin (and Tamoxifen) for almost 2 years since.
That said, if you feel you can go on for another couple of cycles, the benefit should be compounded.
Best wishes.... Pam
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Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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